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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ROS1
All Species:
16.36
Human Site:
S2288
Identified Species:
36
UniProt:
P08922
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08922
NP_002935.2
2347
263915
S2288
C
G
Q
G
E
E
K
S
E
G
P
L
G
S
Q
Chimpanzee
Pan troglodytes
XP_527487
2347
263893
S2288
C
G
Q
G
E
E
K
S
E
G
P
L
G
S
Q
Rhesus Macaque
Macaca mulatta
XP_001110859
2345
263559
S2286
C
S
Q
G
E
E
K
S
E
G
P
L
G
S
Q
Dog
Lupus familis
XP_541215
2048
229894
Q1999
M
D
G
I
F
T
T
Q
S
D
V
W
S
F
G
Cat
Felis silvestris
Mouse
Mus musculus
Q78DX7
2340
261949
Y2281
C
S
Q
G
E
G
S
Y
E
G
P
L
G
P
K
Rat
Rattus norvegicus
Q63132
2338
261637
Y2280
C
S
Q
S
E
D
R
Y
E
G
P
L
G
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518175
2242
244778
L2193
G
H
V
S
R
H
D
L
T
I
E
E
R
L
C
Chicken
Gallus gallus
P08941
2311
260942
E2261
G
F
I
N
Q
A
F
E
D
I
D
V
P
P
A
Frog
Xenopus laevis
O73798
1358
153845
N1309
D
P
S
C
A
L
Q
N
S
E
H
H
A
G
H
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13368
2554
287007
S2495
L
R
R
T
Q
M
A
S
A
T
A
D
T
V
V
Honey Bee
Apis mellifera
XP_394148
2105
237988
R2056
A
L
H
Q
L
M
L
R
C
W
S
D
V
D
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.6
73.4
N.A.
79.8
79.8
N.A.
33.7
53.2
21
N.A.
N.A.
23.1
26.8
N.A.
N.A.
Protein Similarity:
100
99.5
98.2
79.8
N.A.
88.3
87.9
N.A.
47.7
68.7
34.9
N.A.
N.A.
40
45.5
N.A.
N.A.
P-Site Identity:
100
100
93.3
0
N.A.
60
60
N.A.
0
0
0
N.A.
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
93.3
0
N.A.
66.6
80
N.A.
0
20
13.3
N.A.
N.A.
20
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
10
10
0
10
0
10
0
10
0
10
% A
% Cys:
46
0
0
10
0
0
0
0
10
0
0
0
0
0
10
% C
% Asp:
10
10
0
0
0
10
10
0
10
10
10
19
0
10
0
% D
% Glu:
0
0
0
0
46
28
0
10
46
10
10
10
0
0
0
% E
% Phe:
0
10
0
0
10
0
10
0
0
0
0
0
0
10
0
% F
% Gly:
19
19
10
37
0
10
0
0
0
46
0
0
46
10
10
% G
% His:
0
10
10
0
0
10
0
0
0
0
10
10
0
0
10
% H
% Ile:
0
0
10
10
0
0
0
0
0
19
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
28
0
0
0
0
0
0
0
19
% K
% Leu:
10
10
0
0
10
10
10
10
0
0
0
46
0
10
0
% L
% Met:
10
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
46
0
10
19
0
% P
% Gln:
0
0
46
10
19
0
10
10
0
0
0
0
0
0
28
% Q
% Arg:
0
10
10
0
10
0
10
10
0
0
0
0
10
0
0
% R
% Ser:
0
28
10
19
0
0
10
37
19
0
10
0
10
37
0
% S
% Thr:
0
0
0
10
0
10
10
0
10
10
0
0
10
0
10
% T
% Val:
0
0
10
0
0
0
0
0
0
0
10
10
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _